In injectable pharmaceutical packaging, vial sealing is one of the most critical operations. A perfectly sealed vial ensures sterility, tamper evidence, and patient safety, while any inconsistency can lead to contamination, batch rejection, or regulatory non-compliance. Across Great Britain, pharmaceutical manufacturers operating in Cambridge, Oxford, London, Stevenage, Manchester, Liverpool, Nottingham, Leicester, and the wider Midlands life-sciences corridor rely on high-precision vial sealing machines to meet stringent GMP and FDA requirements.
The Vial Cap Sealing Machine from Technogen Enterprise is engineered specifically for these demanding environments. Designed for high-speed, sterile, and wrinkle-free sealing, it delivers consistent performance for injectable packaging lines handling vaccines, antibiotics, hormones, and other critical formulations.
A Vial Cap Sealing Machine is a precision pharmaceutical packaging machine used to crimp aluminium flip-off or tear-off caps onto glass vials. These vials typically contain sterile injectable drugs and must be sealed hermetically to protect product integrity throughout their lifecycle.
The machine applies controlled sealing pressure using advanced mechanical systems to ensure:
Airtight and leak-proof sealing
Tamper-evident closure
Compliance with cGMP, WHO, and US FDA guidelines
Manufactured by Technogen Enterprise, these machines are designed for cleanroom compatibility and isolator integration.
Vial Infeed & Indexing
Vials are fed onto the conveyor and indexed into the rotary platform using star wheel assemblies.
Cap Feeding & Orientation
Aluminium flip-off or tear-off caps are oriented and supplied through a vibrator bowl feeder.
No Vial – No Capping Control
The machine prevents sealing if a vial is absent, eliminating wastage.
Gradual Pressure Sealing (GPS)
Sealing heads apply progressive pressure to crimp the aluminium cap uniformly without wrinkles.
Safety & Jam Detection
Safety clutches stop the machine if vials overturn or jam.
Production Monitoring
An inbuilt counter tracks output for batch control.
Discharge
Properly sealed vials exit smoothly for downstream inspection or labelling.
No Vial – No Capping mechanism
Gradual Pressure Sealing (GPS) system for wrinkle-free seals
Lowest particle generation, suitable for sterile environments
Compact and modular CGMP-compliant design
Stainless steel contact parts (AISI 304)
Quick and tool-less changeover
Adjustable sealing pressure for different cap sizes
Safety clutch system for vial overturning or jamming
CE-certified electrical and mechanical components
| Model | TGVCS-100 | TGVCS-200 | TGVCS-250 | TGVCS-350 |
|---|---|---|---|---|
| Machine Type | 4 Head | 6 Head | 8 Head | 12 Head |
| Sealing Heads | 4 | 6 | 8 | 12 |
| Production Rate | Up to 120 VPM | Up to 180 VPM | Up to 250 VPM | Up to 350 VPM |
| Direction | Left to Right | Left to Right | Left to Right | Left to Right |
| Vial Diameter | Up to 45 mm | Up to 45 mm | Up to 45 mm | Up to 45 mm |
| Vial Height | Up to 75 mm | Up to 75 mm | Up to 75 mm | Up to 75 mm |
| Cap Sizes | 13 mm, 20 mm, 32 mm | 13 mm, 20 mm, 32 mm | 13 mm, 20 mm, 32 mm | 13 mm, 20 mm, 32 mm |
| Speed Control | VFD Assisted | VFD Assisted | VFD Assisted | VFD Assisted |
| Cap Feeding | Vibrator Bowl | Vibrator Bowl | Vibrator Bowl | Vibrator Bowl |
| Electrical Supply | 440 V, 3 Phase, 50 Hz | |||
| Conveyor Height | Adjustable 800–850 mm | |||
| Machine Finish | Stainless Steel Matt Finish |
Toughened glass or acrylic safety cabinet
Tower light for machine status indication
Automatic sealing head up/down adjustment
Pneumatic sealing head with Viton sealing rollers
Raised stopper detection and rejection system
Vision inspection system for seal verification
Online pneumatic rejection system
21 CFR Part 11 compliance
Vacuum-assisted rejection for high-speed lines
The Vial Cap Sealing Machine is widely used across Great Britain in:
Pharmaceutical injectables manufacturing
Vaccine and biologics production
Biotechnology and biosimilars
Veterinary injectables
Diagnostic reagents and laboratory chemicals
Cosmetic serums and specialty liquids
It is particularly suited for pharma hubs in Cambridge–Oxford, London, Midlands, North West England, and South East England.
Hermetic Sealing
Ensures sterility and prevents leakage.
Regulatory Compliance
Designed for GMP, WHO, and FDA standards.
High-Speed Production
Supports up to 350 vials per minute.
Low Particle Generation
Suitable for cleanroom and isolator installations.
Scalable Configuration
Available from 4-head to 12-head models.
Operational Reliability
Built for continuous 24/7 pharmaceutical operations.
Technogen Enterprise is a specialised manufacturer and supplier of pharmaceutical vial sealing machines serving regulated markets worldwide, including Great Britain. Our machines are engineered with a deep understanding of sterile packaging requirements, validation needs, and regulatory expectations.
Pharmaceutical manufacturers across Cambridge, Oxford, London, Stevenage, Manchester, Leicester, Nottingham, and the wider UK life-sciences ecosystem rely on our vial sealing solutions for consistent quality, compliance, and long-term performance.
1. What cap sizes does the machine support?
13 mm, 20 mm, and 32 mm aluminium flip-off or tear-off caps.
2. Is the machine suitable for sterile environments?
Yes, it is designed for cleanroom and isolator applications.
3. What is the maximum production speed?
Up to 350 vials per minute, depending on configuration.
4. Does the machine prevent vial wastage?
Yes, the No Vial–No Capping system eliminates unnecessary sealing.
5. Is this machine suitable for UK pharmaceutical plants?
Yes, it is widely used in pharmaceutical facilities across Great Britain.